Panadol Extra Advance Adverse Reactions

When taken in recommended doses, Panadol Extra Advance is unlikely to cause significant undesirable effects and will not upset the stomach.
Stop taking this medicine and seek medical advice immediately if having: Allergic reactions such as skin rash or itching, sometimes with breathing problems or swelling of the lips, tongue, throat or face; A skin rash or peeling, or mouth ulcers; Previously experienced breathing problems with aspirin or non-steroidal anti-inflammatories, and experienced a similar reaction with this product; Unexplained bruising or bleeding.
Undesirable effects are rare such as: Thrombocytopenia; Anaphylaxis; Cutaneous hypersensitivity reactions including skin rashes, angiodema, and Stevens Johnson Syndrome; Bronchospasm in patients sensitive to aspirin and other NSAIDs; Hepatic dysfunction; Nervousness; Dizziness.
When the recommended Acetaminophen-caffeine dosing regimen is combined with dietary caffeine intake, the resulting higher dose of caffeine may increase the potential for caffeine-related adverse effects such as insomnia, restlessness, anxiety, irritability, headaches, gastrointestinal disturbances and palpitations.